Chronic asymptomatic thrombocytopenia needs more evaluation than treatment

Abstract

Chronic asymptomatic thrombocytopenia (platelet count <150 × 10³/μL for >6 months without bleeding) is an increasingly common incidental finding due to routine laboratory screening. While a low count often triggers clinical concern, data from 2026 indicates that patients with stable counts above 30–50 × 10³/μL rarely experience spontaneous hemorrhage and may not require active treatment. This case demonstrates how a systematic evaluation can identify benign or secondary causes, preventing the risks associated with unnecessary immunosuppression.