Pathological complete response in breast cancer: A case series

Abstract

Background: Pathological Complete Response (pCR) is an important prognostic indicator in oncology, particularly in breast cancer patients receiving neoadjuvant chemotherapy. It is defined as the absence of invasive cancer in the surgical specimen following systemic therapy. Achieving pCR is associated with improved overall survival and disease-free survival. This article presents a case series of patients with breast cancer who achieved pathological complete response following neoadjuvant chemotherapy and subsequent surgical management. They highlight the importance of systemic therapy in achieving tumor regression and improving treatment outcomes.