Reduction in chemoport-related complications following protocol based quality improvement: A single-center audit

Abstract

Background: Totally implantable venous access devices (chemoports) are indispensable in oncology practice but may be associated with infectious, thrombotic, and mechanical complications. We audited our institutional outcomes and assessed whether protocol-based quality improvement reduced complications.

Methods: A retrospective audit of chemoport procedures performed from January 2018 to February 2026 was conducted at a tertiary cancer center. Procedural approach, complications, and outcomes before and after protocol implementation in 2024 were analyzed.

Results: Fifty-four chemoports were inserted and 26 removed. Nineteen complete insertion-removal cases were included for complication analysis. Pre-protocol complication rate was 23.5%, including infections, thrombosis, malrotation, and catheter displacement. After implementation of a standardized protocol, complication rates reduced to 8%, with no malrotation or thrombotic events observed.

Conclusion: Standardized insertion and handling protocols significantly reduced chemoport-related complications and represent a practical quality improvement strategy.